850467-66-2
850467-66-2 structure
- Name: CP 43
- Chemical Name: Compound 43 TAO Kinase Inhibitor
- CAS Number: 850467-66-2
- Molecular Formula: C25H24N2O2
- Molecular Weight: 384.470
- Catalog: Research Areas Cancer
- Create Date: 2019-09-09 15:53:51
- Modify Date: 2025-08-30 12:06:45
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TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death[1].
| Name | Compound 43 TAO Kinase Inhibitor |
|---|---|
| Synonyms |
[1,1'-Biphenyl]-4-carboxamide, N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-
MFCD15612807 N-[2-Oxo-2-(1,2,3,4-tetrahydro-1-naphthalenylamino)ethyl]-4-biphenylcarboxamide TAOK inhibitor 43 |
| Description | TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death[1]. |
|---|---|
| Related Catalog | |
| In Vitro | TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death in centrosome amplified breast cancer cells[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 673.2±54.0 °C at 760 mmHg |
| Molecular Formula | C25H24N2O2 |
| Molecular Weight | 384.470 |
| Flash Point | 224.7±31.4 °C |
| Exact Mass | 384.183777 |
| LogP | 5.37 |
| Appearance | solid |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.647 |
| Storage condition | Store at -20°C |
| Water Solubility | Soluble in DMSO |