133229-11-5

133229-11-5 structure

Name: AM 92016
Chemical Name: AM-92016 hydrochloride
CAS Number: 133229-11-5
Molecular Formula: C₁₉H₂₅Cl₃N₂O₄S
Molecular Weight: 483.84
Catalog: Research Areas Cardiovascular Disease
Create Date: 2019-09-07 12:12:18
Modify Date: 2024-01-04 18:41:06
AM 92016 (hydrochloride) is a specific IK inhibitor. AM 92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM[1].

Name	AM-92016 hydrochloride

Description	AM 92016 (hydrochloride) is a specific IK inhibitor. AM 92016 (hydrochloride) delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse. AM 92016 (hydrochloride) prolongs cardiac action potential duration in guinea-pig and rabbit isolated ventricular cells with an IC50 of 30 nM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. ConnorsSP,etal.Actions and mechanisms of action of novel analogues of sotalol on guinea-pig and rabbitventricular cells. Br J Pharmacol. 1992 Aug;106(4):958-65.

Molecular Formula	C₁₉H₂₅Cl₃N₂O₄S
Molecular Weight	483.84