2267329-76-8
2267329-76-8 structure
- Name: Egfr-IN-7(TQB3804 )
- Chemical Name: EGFR-IN-7
- CAS Number: 2267329-76-8
- Molecular Formula: C32H41BrN9O2P
- Molecular Weight: 694.60
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2019-09-10 12:25:48
- Modify Date: 2024-01-06 16:56:36
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EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1].
| Name | EGFR-IN-7 |
|---|
| Description | EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFR (WT):7.92 nM (IC50) EGFR (C797S/T790M/L858R):0.218 nM (IC50) |
| References |
[1]. Aryl-phosphorus-oxygen compound as egfr kinase inhibitor. |
| Molecular Formula | C32H41BrN9O2P |
|---|---|
| Molecular Weight | 694.60 |