1314796-00-3
1314796-00-3 structure
- Name: hGPR91 antagonist 1
- Chemical Name: hGPR91 antagonist 1
- CAS Number: 1314796-00-3
- Molecular Formula: C31H23F4N3O
- Molecular Weight: 529.53
- Catalog: Research Areas Others
- Create Date: 2019-09-09 18:19:51
- Modify Date: 2024-01-13 22:10:32
-
HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM[1].
| Name | hGPR91 antagonist 1 |
|---|
| Description | HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 7 μM (HGPR91)[1] |
| In Vivo | HGPR91 antagonist 1 leads to 59, 76% inhibition of ΔMAP at 2, 4 hours and has shown rat plasma protein binding 99%. HGPR91 antagonist 1 has engaged the target under the in vivo condition. HGPR91 antagonist 1 has clearance (CL) of 0.2 nmol/min/mg of RLM[1]. Animal Model: Wistar rats[1] Dosage: 100 mg/kg Administration: I.p.; 2 and 4 hours Result: Led to 59 and 76% inhibition of ΔMAP at 2 and 4 hours. |
| References |
| Molecular Formula | C31H23F4N3O |
|---|---|
| Molecular Weight | 529.53 |