2358775-67-2

2358775-67-2 structure

Name: Bis-PEG1-C-PEG1-CH2COOH
Chemical Name: PROTAC Linker 26
CAS Number: 2358775-67-2
Molecular Formula: C₁₆H₃₀O₈
Molecular Weight: 350.40
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-09-07 16:25:19
Modify Date: 2024-02-04 19:35:00
PROTAC Linker 26 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 26 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	PROTAC Linker 26

Description	PROTAC Linker 26 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 26 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.