1263819-48-2

1263819-48-2 structure

Name: NH2-Ph-C4-acid-NH2-Me
Chemical Name: PROTAC Linker 31
CAS Number: 1263819-48-2
Molecular Formula: C₁₂H₁₈N₂O₂
Molecular Weight: 222.28
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-10-08 11:15:52
Modify Date: 2024-01-11 00:13:02
PROTAC Linker 31 is a PROTAC linker, which refers to the Alkyl-Chain composition. PROTAC Linker 31 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	PROTAC Linker 31

Description	PROTAC Linker 31 is a PROTAC linker, which refers to the Alkyl-Chain composition. PROTAC Linker 31 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
References	[1]. Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.