Shanghai Nianxing Industrial Co., Ltd
China
Product Name: RAF mutant-IN-1
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2340020-82-6

2340020-82-6 structure

2340020-82-6 structure

Name: RAF mutant-IN-1
Chemical Name: RAF mutant-IN-1
CAS Number: 2340020-82-6
Molecular Formula: C₂₃H₁₈Cl₃FN₆O₂S
Molecular Weight: 567.85
Catalog: Signaling Pathways MAPK/ERK Pathway Raf
Create Date: 2019-10-09 13:09:29
Modify Date: 2024-01-05 18:30:41
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].

Name	RAF mutant-IN-1

Description	RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	C-RAF 340D/Y341D:21 nM (IC50) B-RafV600E:30 nM (IC50) BRAFWT:392 nM (IC50)
References	[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.

Molecular Formula	C₂₃H₁₈Cl₃FN₆O₂S
Molecular Weight	567.85