2246380-70-9

2246380-70-9 structure
2246380-70-9 structure

Name Stabilized lactone
Description Stabilized lactone (Drug linker 2) is a stabilized lactone-linked SN-38 drug linker. Stabilized lactone is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].
Related Catalog
References

[1]. Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072.

Molecular Formula C50H54N6O20S
Molecular Weight 1091.06
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