2378258-52-5

2378258-52-5 structure

Name: PROTAC K-Ras Degrader-1
Chemical Name: PROTAC K-Ras Degrader-1
CAS Number: 2378258-52-5
Molecular Formula: C₅₃H₆₂N₁₀O₁₀
Molecular Weight: 999.12
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2019-12-08 16:19:19
Modify Date: 2025-08-24 21:49:11
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].

Name	PROTAC K-Ras Degrader-1

Description	PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> PROTAC >> PROTAC
Target	KRAS(G12C) Cereblon
References	[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.