2376328-55-9
2376328-55-9 structure
- Name: K-Ras G12C-IN-4
- Chemical Name: K-Ras G12C-IN-4
- CAS Number: 2376328-55-9
- Molecular Formula: C31H33ClN4O4
- Molecular Weight: 561.07
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2019-12-08 18:48:19
- Modify Date: 2024-01-15 11:55:37
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K-Ras G12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRASG12C[1].
| Name | K-Ras G12C-IN-4 |
|---|
| Description | K-Ras G12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRASG12C[1]. |
|---|---|
| Related Catalog | |
| In Vitro | K-Ras G12C-IN-4 (4 hours) exhibits IC50=0.219 μM for inhibition of MAPK signaling (p-ERK) in MIA PaCa-2 cells[1]. K-Ras G12C-IN-4 (72 hours) translates to a 0.067 μM IC50 for inhibition of cellular viability in a CellTiter-Glo experiment in MIA PaCa-2 cells[1]. |
| References |
| Molecular Formula | C31H33ClN4O4 |
|---|---|
| Molecular Weight | 561.07 |