1201652-50-7
1201652-50-7 structure
- Name: Retro 2
- Chemical Name: 2-{(E)-[(5-Methyl-2-thienyl)methylene]amino}-N-phenylbenzamide
- CAS Number: 1201652-50-7
- Molecular Formula: C19H16N2OS
- Molecular Weight: 320.408
- Create Date: 2020-01-11 18:05:57
- Modify Date: 2024-02-05 11:51:43
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Retro 2 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.
| Name | 2-{(E)-[(5-Methyl-2-thienyl)methylene]amino}-N-phenylbenzamide |
|---|---|
| Synonyms |
2-{(E)-[(5-Methyl-2-thienyl)methylene]amino}-N-phenylbenzamide
2-{[(E)-(5-methylthiophen-2-yl)methylidene]amino}-N-phenylbenzamide MFCD01042512 Benzamide, 2-[[(1E)-(5-methyl-2-thienyl)methylene]amino]-N-phenyl- |
| Description | Retro 2 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge. |
|---|---|
| References | References 1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42. View Related Products by Target Other Targets |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 461.9±40.0 °C at 760 mmHg |
| Molecular Formula | C19H16N2OS |
| Molecular Weight | 320.408 |
| Flash Point | 233.2±27.3 °C |
| Exact Mass | 320.098328 |
| LogP | 4.16 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.629 |