1883548-88-6

1883548-88-6 structure

Name: FFN 206 dihydrochloride
Chemical Name: 4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride
CAS Number: 1883548-88-6
Molecular Formula: C₁₂H₁₆Cl₂N₂O₂
Molecular Weight: 291.174
Catalog: Research Areas Others
Create Date: 2020-01-12 16:08:48
Modify Date: 2024-04-08 19:12:48
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture.

Name	4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride
Synonyms	4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one dihydrochloride 2H-1-Benzopyran-2-one, 4-(2-aminoethyl)-7-(methylamino)-, hydrochloride (1:2)

Description	FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture.
References	References 1. Hu G, et al. ACS Chem Biol. 2013 Sep 20;8(9):1947-54. View Related Products by Target Monoamine Transporter