2131223-69-1

2131223-69-1 structure

Name: YW1159
Chemical Name: 1-(2-Fluorophenyl)-5-methyl-N-(2-quinolinyl)-1H-1,2,3-triazole-4-carboxamide
CAS Number: 2131223-69-1
Molecular Formula: C₁₉H₁₄FN₅O
Molecular Weight: 347.346
Create Date: 2020-01-12 12:08:32
Modify Date: 2024-01-12 15:44:08
YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.

Name	1-(2-Fluorophenyl)-5-methyl-N-(2-quinolinyl)-1H-1,2,3-triazole-4-carboxamide
Synonyms	1-(2-Fluorophenyl)-5-methyl-N-(2-quinolinyl)-1H-1,2,3-triazole-4-carboxamide 1H-1,2,3-Triazole-4-carboxamide, 1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-

Description	YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.
In Vitro	YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.