244101-03-9
244101-03-9 structure
- Name: MF266-3
- Chemical Name: L-826266
- CAS Number: 244101-03-9
- Molecular Formula: C27H21BrClNO4S
- Molecular Weight: 570.882
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2020-01-11 19:24:30
- Modify Date: 2024-04-05 22:07:53
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MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM; displayes a relatively good selectivity over other prostanoid receptors.
| Name | L-826266 |
|---|---|
| Synonyms |
(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthylmethyl)phenyl]acrylamide
2-Propenamide, N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[5-chloro-2-(2-naphthalenylmethyl)phenyl]-, (2E)- L-826266 |
| Description | MF266-3 is a potent, selective prostaglandin E receptor subtype 3 (EP3) antagonist with Ki of 0.8 nM; displayes a relatively good selectivity over other prostanoid receptors. |
|---|---|
| References | References 1. Clark P. et al. J Pharmacol Exp Ther. 2008 May;325(2):425-34. 2. Juteau H, et al. Bioorg Med Chem. 2001 Aug;9(8):1977-84. View Related Products by Target Prostaglandin Receptor |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H21BrClNO4S |
| Molecular Weight | 570.882 |
| Exact Mass | 569.006287 |
| LogP | 8.29 |
| Index of Refraction | 1.662 |