674359-78-5
674359-78-5 structure
- Name: CID3528206
- Chemical Name: N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine
- CAS Number: 674359-78-5
- Molecular Formula: C11H11FN6O2
- Molecular Weight: 278.242
- Create Date: 2020-01-12 17:19:22
- Modify Date: 2024-10-06 13:49:44
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CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.
| Name | N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine |
|---|---|
| Synonyms |
N4-(3-Fluorophenyl)-N2-methyl-5-nitro-2,4,6-pyrimidinetriamine
N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine 2,4,6-Pyrimidinetriamine, N4-(3-fluorophenyl)-N2-methyl-5-nitro- |
| Description | CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth. |
|---|---|
| References | References 1. Chen J, et al. ACS Chem Biol. 2012 Apr 20;7(4):715-22. View Related Products by Target mTOR |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 493.9±55.0 °C at 760 mmHg |
| Molecular Formula | C11H11FN6O2 |
| Molecular Weight | 278.242 |
| Flash Point | 252.5±31.5 °C |
| Exact Mass | 278.092743 |
| LogP | 1.91 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.736 |