1008671-41-7
1008671-41-7 structure
- Name: SPI009
- Chemical Name: 1-{[2-(2,4-Dichlorophenyl)ethyl]amino}-3-phenoxy-2-propanol
- CAS Number: 1008671-41-7
- Molecular Formula: C17H19Cl2NO2
- Molecular Weight: 340.244
- Create Date: 2020-01-11 20:41:09
- Modify Date: 2024-01-11 12:30:26
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SPI009 is a novel antipersister compound active against P. aeruginosa; reduces the number of persisters up to 100,000-fold in both lab strains and clinical isolates of P. aeruginosa when combined with distinct classes of antibiotics; efficiently kills persister cells with minor cytotoxicity, and causes no erythrocyte damage.
| Name | 1-{[2-(2,4-Dichlorophenyl)ethyl]amino}-3-phenoxy-2-propanol |
|---|---|
| Synonyms |
1-{[2-(2,4-Dichlorophenyl)ethyl]amino}-3-phenoxy-2-propanol
MFCD05261333 2-Propanol, 1-[[2-(2,4-dichlorophenyl)ethyl]amino]-3-phenoxy- |
| Description | SPI009 is a novel antipersister compound active against P. aeruginosa; reduces the number of persisters up to 100,000-fold in both lab strains and clinical isolates of P. aeruginosa when combined with distinct classes of antibiotics; efficiently kills persister cells with minor cytotoxicity, and causes no erythrocyte damage. |
|---|---|
| References | References 1. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00836-17. 2. Defraine V, et al. Front Microbiol. 2017 Dec 22;8:2585. View Related Products by Target Bacterial |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 494.7±45.0 °C at 760 mmHg |
| Molecular Formula | C17H19Cl2NO2 |
| Molecular Weight | 340.244 |
| Flash Point | 253.0±28.7 °C |
| Exact Mass | 339.079285 |
| LogP | 4.38 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.586 |