1258076-66-2
1258076-66-2 structure
- Name: T3D-959
- Chemical Name: Sodium [(1S)-5-{2-[5-ethyl-2-(4-methoxyphenyl)-1,3-oxazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetate
- CAS Number: 1258076-66-2
- Molecular Formula: C25H26NNaO5
- Molecular Weight: 443.467
- Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
- Create Date: 2020-01-19 22:38:56
- Modify Date: 2024-01-11 22:23:26
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T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively; prevents STZ-induced neurotoxicity, and shows clear therapeutic and neuroprotective effects in an established model of sporadic AD. Alzheimer Disease Phase 2 Clinical
| Name | Sodium [(1S)-5-{2-[5-ethyl-2-(4-methoxyphenyl)-1,3-oxazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetate |
|---|---|
| Synonyms |
Sodium [(1S)-5-{2-[5-ethyl-2-(4-methoxyphenyl)-1,3-oxazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl]acetate
1H-Indene-1-acetic acid, 5-[2-[5-ethyl-2-(4-methoxyphenyl)-4-oxazolyl]ethoxy]-2,3-dihydro-, sodium salt, (1S)- (1:1) |
| Description | T3D 959 (DB-959) is a potent, brain penetrant, orally active dual PPARδ/PPARγ agonist with EC50 of 19/297 nM, respectively; prevents STZ-induced neurotoxicity, and shows clear therapeutic and neuroprotective effects in an established model of sporadic AD. Alzheimer Disease Phase 2 Clinical |
|---|---|
| References | References 1. Tong M, et al. J Alzheimers Dis. 2016;51(1):123-38. 2. Tong M, et al. J Alzheimers Dis Parkinsonism. 2016 Jun;6(3). pii: 238. View Related Products by Target PPAR Alzheimer Disease |
| Molecular Formula | C25H26NNaO5 |
|---|---|
| Molecular Weight | 443.467 |
| Exact Mass | 443.170868 |