1374128-90-1
1374128-90-1 structure
- Name: Vitacoxib
- Chemical Name: 2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine
- CAS Number: 1374128-90-1
- Molecular Formula: C16H14ClN3O2S
- Molecular Weight: 347.819
- Create Date: 2020-01-11 16:58:50
- Modify Date: 2024-09-17 08:45:39
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A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use.
| Name | 2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine |
|---|---|
| Synonyms |
Pyridine, 2-[4-chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)-
2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine |
| Description | A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use. |
|---|---|
| References | References 1. Wang J, et al. Regul Toxicol Pharmacol. 2017 Jun;86:49-58. 2. Wang J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:270-274. View Related Products by Target Cyclooxygenase (COX) |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.1±50.0 °C at 760 mmHg |
| Molecular Formula | C16H14ClN3O2S |
| Molecular Weight | 347.819 |
| Flash Point | 305.9±30.1 °C |
| Exact Mass | 347.049530 |
| LogP | 1.87 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.655 |