Name | 6,6'-(4-Nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one) |
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Synonyms |
Pyrazolo[1,5-a]pyrimidin-2(1H)-one, 6,6'-(4-nitro-1H-pyrazole-3,5-diyl)bis[3-bromo-
6,6'-(4-Nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one) |
Description | ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens. |
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References | References 1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18. View Related Products by Target Bacterial |
Density | 2.6±0.1 g/cm3 |
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Molecular Formula | C15H7Br2N9O4 |
Molecular Weight | 537.082 |
Exact Mass | 534.898743 |
LogP | 0.00 |
Index of Refraction | 2.068 |