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904579-65-3

904579-65-3 structure
904579-65-3 structure
  • Name: 1835F03
  • Chemical Name: 7-Chloro-N,N-diethyl-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
  • CAS Number: 904579-65-3
  • Molecular Formula: C19H18ClN5O2S
  • Molecular Weight: 415.897
  • Create Date: 2020-01-11 15:44:52
  • Modify Date: 2024-10-12 12:07:31
  • 1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates.

Name 7-Chloro-N,N-diethyl-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
Synonyms 7-Chloro-N,N-diethyl-3-(phenylsulfonyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine
[1,2,3]Triazolo[1,5-a]quinazolin-5-amine, 7-chloro-N,N-diethyl-3-(phenylsulfonyl)-
Description 1835F03 is a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus, inhibits the growth of a panel of S aureus strains (MIC=1-3 ug/mL), including clinical MRSA isolates.
References References 1. Swoboda JG, et al. ACS Chem Biol. 2009 Oct 16;4(10):875-83. 2. Lee K, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1767-70. 3. Suzuki T, et al. Antimicrob Agents Chemother. 2011 Feb;55(2):767-74. View Related Products by Target Bacterial
Density 1.4±0.1 g/cm3
Molecular Formula C19H18ClN5O2S
Molecular Weight 415.897
Exact Mass 415.086975
LogP 3.84
Index of Refraction 1.698
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