1454584-91-8
1454584-91-8 structure
- Name: SR-2890
- Chemical Name: SR-2890
- CAS Number: 1454584-91-8
- Molecular Formula: C23H21ClFN9
- Molecular Weight: 477.932
- Create Date: 2020-01-12 19:31:47
- Modify Date: 2026-04-25 00:26:37
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A potent, highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 4 nM for CK1δ; inhibits melanoma A375 cell growth with EC50 of 38 nM in MTT assays, has physical, in vitro and in vivo PK properties suitable for use in proof of principle animal xenograft studies against human cancer cell lines.
| Name | SR-2890 |
|---|
| Description | A potent, highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 4 nM for CK1δ; inhibits melanoma A375 cell growth with EC50 of 38 nM in MTT assays, has physical, in vitro and in vivo PK properties suitable for use in proof of principle animal xenograft studies against human cancer cell lines. |
|---|---|
| References | References 1. Bibian M, et al. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4374-80. View Related Products by Target Casein Kinase |
| Molecular Formula | C23H21ClFN9 |
|---|---|
| Molecular Weight | 477.932 |