2041075-86-7
2041075-86-7 structure
- Name: AZD5718
- Chemical Name: AZD5718
- CAS Number: 2041075-86-7
- Molecular Formula: C24H26N6O3
- Molecular Weight: 446.511
- Create Date: 2020-01-19 20:20:55
- Modify Date: 2025-08-25 11:34:40
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AZD5718 (AZD-5718, AZD 5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM; exhibits LTB4 inhibition in human whole blood assays with IC50 of 39 nM; reduce the production of pro-inflammatory and vasoactive leukotrienes both in vitro and in vivo.
| Name | AZD5718 |
|---|
| Description | AZD5718 (AZD-5718, AZD 5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM; exhibits LTB4 inhibition in human whole blood assays with IC50 of 39 nM; reduce the production of pro-inflammatory and vasoactive leukotrienes both in vitro and in vivo. |
|---|---|
| References | References 1. Ericsson H, et al. Clin Transl Sci. 2018 May;11(3):330-338. 2. Pettersen D, et al. J Med Chem. 2019 Mar 14. doi: 10.1021/acs.jmedchem.8b02004. View Related Products by Target FLAP |
| Molecular Formula | C24H26N6O3 |
|---|---|
| Molecular Weight | 446.511 |