1069858-99-6
1069858-99-6 structure
- Name: ML359
- Chemical Name: ML359
- CAS Number: 1069858-99-6
- Molecular Formula: C23H28ClNO4
- Molecular Weight: 417.93
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-01-19 20:39:55
- Modify Date: 2025-07-25 14:57:26
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ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.
| Name | ML359 |
|---|
| Description | ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro. |
|---|---|
| References | References 1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target Protein Disulfide Isomerase (PDI) |
| Molecular Formula | C23H28ClNO4 |
|---|---|
| Molecular Weight | 417.93 |
| Storage condition | 2-8°C |