Name | ML379 |
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Description | ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant); displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type); displays low nM activity in a larger panel of TP53 mutant cell lines. |
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References | References 1. Lewis TA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target MDM2-p53 |
Molecular Formula | C15H19N3O2 |
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Molecular Weight | 273.33 |