Name | PDE2 inhibitor 4 |
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Description | PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms; exhibits excellent pharmacokinetic properties in multiple species and improves cognitive performance in both the rat Novel Object Recognition and rhesus Object Recognition assays. |
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References | References 1. Stachel SJ, et al. ACS Med Chem Lett. 2018 Jul 26;9(8):815-820. View Related Products by Target Phosphodiesterase (PDE) |
Molecular Formula | C16H15F3N4O2 |
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Molecular Weight | 352.317 |