Top Suppliers:I want be here


2170170-27-9

2170170-27-9 structure
2170170-27-9 structure
  • Name: SOD1-Derlin-1 inhibitor 56-59
  • Chemical Name: SOD1-Derlin-1 inhibitor 56-59
  • CAS Number: 2170170-27-9
  • Molecular Formula: C22H18N4OS
  • Molecular Weight: 386.473
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2020-01-11 16:16:53
  • Modify Date: 2024-01-22 08:59:51
  • SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay; significantly ameliorates the ALS pathology both in motoneurons derived from patient induced pluripotent stem cells and in model mice.

Name SOD1-Derlin-1 inhibitor 56-59
Description SOD1-Derlin-1 inhibitor 56-59 is a cell-permeable, small molecule inhibitor of SOD1-Derlin-1 interaction, target SOD1 DBR and clearly attenuates the interactions of Derlin-1 with 122 types of SOD1mut in the cell-based co-immunoprecipitation assay; significantly ameliorates the ALS pathology both in motoneurons derived from patient induced pluripotent stem cells and in model mice.
References References 1. Tsuburaya N, et al. Nat Commun. 2018 Jul 10;9(1):2668. View Related Products by Target Other Targets
Molecular Formula C22H18N4OS
Molecular Weight 386.473
Storage condition -20°C