327613-10-5
327613-10-5 structure
- Name: BIO-7662
- Chemical Name: BIO-7662
- CAS Number: 327613-10-5
- Molecular Formula: C38H48N6O8S
- Molecular Weight: 748.896
- Catalog: Signaling Pathways Cytoskeleton Integrin
- Create Date: 2020-01-12 10:01:50
- Modify Date: 2026-07-15 17:51:38
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A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM; the rate of BIO7662 binding is dependent on the metal ion concentration; directly competes with VCAM-1, CS-1, and BIO1211 for binding to the integrin.
| Name | BIO-7662 |
|---|---|
| Synonyms |
Butanoic acid, 4-[[(2S)-4-methyl-2-[methyl[[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]-2-[[[(2S)-1-(phenylsulfonyl)-2-pyrrolidinyl]carbonyl]amino]-, (2S)- (9CI)
BIO-7662 (BIO |
| Description | A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM; the rate of BIO7662 binding is dependent on the metal ion concentration; directly competes with VCAM-1, CS-1, and BIO1211 for binding to the integrin. |
|---|---|
| References | References 1. Chen LL, et al. J Biol Chem. 2001 Sep 28;276(39):36520-9. 2. Egger LA, et al. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. View Related Products by Target Integrin |
| Molecular Formula | C38H48N6O8S |
|---|---|
| Molecular Weight | 748.896 |