940954-41-6
940954-41-6 structure
- Name: BI-1935
- Chemical Name: BI-1935
- CAS Number: 940954-41-6
- Molecular Formula: C24H21F3N6O3
- Molecular Weight: 498.466
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-01-11 19:04:50
- Modify Date: 2024-01-09 12:57:07
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BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.
| Name | BI-1935 |
|---|
| Description | BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2. |
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| References | References View Related Products by Target Other Targets |
| Molecular Formula | C24H21F3N6O3 |
|---|---|
| Molecular Weight | 498.466 |