1435727-97-1

1435727-97-1 structure

Name: Duloxetine D3 hydrochloride
Chemical Name: Duloxetine D3 hydrochloride
CAS Number: 1435727-97-1
Molecular Formula: C₁₈H₁₇D₃ClNOS
Molecular Weight: 336.89
Catalog: Signaling Pathways Neuronal Signaling Serotonin Transporter
Create Date: 2020-01-23 21:32:51
Modify Date: 2026-07-16 13:03:31
Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].

Name	Duloxetine D3 hydrochloride
Synonyms	(S)-Duloxetine D3 hydrochloride Duloxetine-D3.HCl, 0.1mg/ml in Methanol (as free base) Duloxetine Hydrochloride D3 Duloxetine-D3.HCl, 1mg/ml in Methanol (as free base) LY248686 D3 hydrochloride

Description	Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter
References	[1]. De Berardis, D., et al., The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature. Int J Immunopathol Pharmacol, 2010. 23(2): p. 417-22. [2]. Wang, S.Y., J. Calderon, and G. Kuo Wang, Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner. Anesthesiology, 2010. 113(3): p. 655-65.

Molecular Formula	C₁₈H₁₇D₃ClNOS
Molecular Weight	336.89