Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TSHR antagonist S37
Price: Check
Purity: 98.35%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TSHR antagonist S37
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: TSHR antagonist S37
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

1217616-61-9

1217616-61-9 structure

1217616-61-9 structure

Name: TSHR antagonist S37
Chemical Name: TSHR antagonist S37
CAS Number: 1217616-61-9
Molecular Formula: C₂₅H₂₀N₂O₃S₂
Molecular Weight: 460.57
Catalog: Signaling Pathways GPCR/G Protein TSH Receptor
Create Date: 2020-01-24 08:12:51
Modify Date: 2024-01-07 11:14:54
TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a[1].

Name	TSHR antagonist S37

Description	TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> TSH Receptor
Target	TSHR[1]
In Vitro	TSHR antagonist S37 reduces also cAMP activation induced by the small molecule agonist C2[1]. TSHR antagonist S37 (10-100 µM) does not affect cell viability in the concentration range for the Hek293T-TSHR cell line[1].
References	[1]. Marcinkowski P, et al. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy. Thyroid. 2019 Jan;29(1):111-123.

Molecular Formula	C₂₅H₂₀N₂O₃S₂
Molecular Weight	460.57

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