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1689540-62-2

1689540-62-2 structure
1689540-62-2 structure
  • Name: αvβ1 integrin-IN-1
  • Chemical Name: αvβ1 integrin-IN-1
  • CAS Number: 1689540-62-2
  • Molecular Formula: C26H34N6O6S
  • Molecular Weight: 558.65
  • Catalog: Signaling Pathways Cytoskeleton Integrin
  • Create Date: 2020-01-23 13:21:51
  • Modify Date: 2024-01-12 08:42:18
  • αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].

Name αvβ1 integrin-IN-1
Description αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].
Related Catalog
Target

IC50: 0.63 nM (αvβ1 integrin)[1]

In Vitro αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis[1].
References

[1]. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.

Molecular Formula C26H34N6O6S
Molecular Weight 558.65