756525-97-0

756525-97-0 structure
756525-97-0 structure
  • Name: Biotin-PEG4-Hydrazide
  • Chemical Name: Biotin-PEG4-hydrazide
  • CAS Number: 756525-97-0
  • Molecular Formula: C21H39N5O7S
  • Molecular Weight: 505.63
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-13 09:28:35
  • Modify Date: 2024-01-10 10:42:35
  • Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG4-hydrazide
Synonyms MFCD09952658
Description Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula C21H39N5O7S
Molecular Weight 505.63
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