1085938-09-5

1085938-09-5 structure
1085938-09-5 structure
  • Name: Biotin-PEG6-azide
  • Chemical Name: Biotin-PEG6-azide
  • CAS Number: 1085938-09-5
  • Molecular Formula: C24H44N6O8S
  • Molecular Weight: 576.71
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-13 18:01:28
  • Modify Date: 2024-01-11 06:56:59
  • Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG6-azide
Description Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula C24H44N6O8S
Molecular Weight 576.71