Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Biotin-PEG8-acid
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Purity: 98.0%
Stocking Period: 10 Day
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Email: sales@echemcloud.com

2143964-62-7

2143964-62-7 structure

2143964-62-7 structure

Name: Biotin-PEG8-acid
Chemical Name: Biotin-PEG8-acid
CAS Number: 2143964-62-7
Molecular Formula: C₂₉H₅₃N₃O₁₂S
Molecular Weight: 667.81
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 09:25:45
Modify Date: 2024-01-10 17:02:51
Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG8-acid
Synonyms	MFCD26127802

Description	Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula	C₂₉H₅₃N₃O₁₂S
Molecular Weight	667.81

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