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850559-51-2

850559-51-2 structure
850559-51-2 structure
  • Name: BMVC2
  • Chemical Name: BMVC2
  • CAS Number: 850559-51-2
  • Molecular Formula: C28H25I2N3
  • Molecular Weight: 657.33
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage G-quadruplex
  • Create Date: 2020-04-05 23:40:58
  • Modify Date: 2024-01-02 11:30:21
  • BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].

Name BMVC2
Description BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].
Related Catalog
Target

G-quadruplex[1]

In Vitro BMVC2 by monitoring the disappearance of the 291 nm CD signals of d[AG3(T2AG3)3] (HT22) after adding Cu2+ is screened, a longer unfolding time would dictate a better G4 stabilizer. The unfolding curve of HT22 in the presence of BMVC2 can be fitted by using two time constants of 133.7 s (29%) and 2816 s (71%), which are similar to the unfolding parameters of BMVC[1].
References

[1]. Jen-Fei Chu, et al. A Novel Method for Screening G-quadruplex Stabilizers to Human Telomeres. Journal of the Chinese Chemical Society, 2011, 58, 296-300.

Molecular Formula C28H25I2N3
Molecular Weight 657.33
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