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918132-15-7

918132-15-7 structure
918132-15-7 structure
  • Name: t-Boc-Aminooxy-PEG3-bromide
  • Chemical Name: Boc-Aminooxy-PEG3-bromide
  • CAS Number: 918132-15-7
  • Molecular Formula: C13H26BrNO6
  • Molecular Weight: 372.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-08 17:02:00
  • Modify Date: 2024-01-11 13:05:30
  • Boc-Aminooxy-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-Aminooxy-PEG3-bromide
Synonyms MFCD29764337
Description Boc-Aminooxy-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C13H26BrNO6
Molecular Weight 372.25