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1895922-77-6

1895922-77-6 structure
1895922-77-6 structure
  • Name: t-Boc-aminooxy-PEG4-propargyl
  • Chemical Name: Boc-aminooxy-PEG4-propargyl
  • CAS Number: 1895922-77-6
  • Molecular Formula: C16H29NO7
  • Molecular Weight: 347.40
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-07 11:21:58
  • Modify Date: 2024-01-10 23:03:31
  • Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-aminooxy-PEG4-propargyl
Synonyms MFCD29764340
Description Boc-aminooxy-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C16H29NO7
Molecular Weight 347.40