2250216-94-3

2250216-94-3 structure

2250216-94-3 structure

Name: tert-Butyl ((17-amino-3,6,9,12,15-pentaoxaheptadecyl)oxy)carbamate
Chemical Name: Boc-Aminooxy-PEG5-amine
CAS Number: 2250216-94-3
Molecular Formula: C₁₇H₃₆N₂O₈
Molecular Weight: 396.48
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-04 21:31:32
Modify Date: 2024-01-16 12:37:24
Boc-Aminooxy-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-Aminooxy-PEG5-amine

Description	Boc-Aminooxy-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula	C₁₇H₃₆N₂O₈
Molecular Weight	396.48

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