2055014-69-0

2055014-69-0 structure

Name: Fluorescein-PEG6-Acid
Chemical Name: Fluorescein-thiourea-PEG6-acid
CAS Number: 2055014-69-0
Molecular Formula: C₃₆H₄₂N₂O₁₃S
Molecular Weight: 742.79
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 14:32:19
Modify Date: 2024-01-02 17:54:16
Fluorescein-thiourea-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fluorescein-thiourea-PEG6-acid

Description	Fluorescein-thiourea-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562