248275-10-7

248275-10-7 structure

Name: Aminooxy-PEG3-methane
Chemical Name: m-PEG3-Aminooxy
CAS Number: 248275-10-7
Molecular Formula: C₇H₁₇NO₄
Molecular Weight: 179.21
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-08 11:25:36
Modify Date: 2024-01-10 21:35:14
m-PEG3-Aminooxy is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG3-Aminooxy

Description	m-PEG3-Aminooxy is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Luo W, et al. Tailored electroactive and quantitative ligand density microarrays applied to stem cell differentiation. J Am Chem Soc. 2010 Mar 3;132(8):2614-21.