2055040-85-0

2055040-85-0 structure

Name: m-PEG3-S-PEG4-propargyl
Chemical Name: m-PEG3-S-PEG4-propargyl
CAS Number: 2055040-85-0
Molecular Formula: C₁₈H₃₄O₇S
Molecular Weight: 394.52
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-12 15:23:08
Modify Date: 2024-01-10 09:47:45
m-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG3-S-PEG4-propargyl

Description	m-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.