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90784-86-4

90784-86-4 structure
90784-86-4 structure
  • Name: m-PEG6-2-methylacrylate
  • Chemical Name: m-PEG6-2-methylacrylate
  • CAS Number: 90784-86-4
  • Molecular Formula: C17H32O8
  • Molecular Weight: 364.43
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-14 18:32:55
  • Modify Date: 2024-01-10 17:35:30
  • m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name m-PEG6-2-methylacrylate
Description m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhu C, et al. Reversibly shielded DNA polyplexes based on bioreducible PDMAEMA-SS-PEG-SS-PDMAEMA triblock copolymers mediate markedly enhanced nonviral gene transfection. Biomacromolecules. 2012 Mar 12;13(3):769-78.

Molecular Formula C17H32O8
Molecular Weight 364.43