2226733-37-3

2226733-37-3 structure
2226733-37-3 structure
  • Name: Mal-PEG24-NHS ester
  • Chemical Name: Mal-PEG24-NHS ester
  • CAS Number: 2226733-37-3
  • Molecular Formula: C16H19N3O8
  • Molecular Weight: 381.34
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-07 15:11:32
  • Modify Date: 2024-01-11 16:48:48
  • Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG24-NHS ester
Description Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C16H19N3O8
Molecular Weight 381.34