Name | Propargyl-PEG9-amine |
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Description | Propargyl-PEG9-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
References |
[1]. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1. |
Molecular Formula | C21H41NO9 |
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Molecular Weight | 451.55 |
Storage condition | 2-8°C |