2360533-90-8

2360533-90-8 structure

Name: PROTAC IRAK4 degrader-1
Chemical Name: PROTAC IRAK4 degrader-1
CAS Number: 2360533-90-8
Molecular Formula: C₄₄H₃₉F₃N₁₂O₇
Molecular Weight: 904.85
Catalog: Signaling Pathways Immunology/Inflammation IRAK
Create Date: 2020-04-07 18:35:26
Modify Date: 2025-08-20 20:37:44
PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes <20%, >20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].

Name	PROTAC IRAK4 degrader-1

Description	PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes <20%, >20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> IRAK Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK
Target	IRAK4 Cereblon
References	[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.