1631754-41-0

1631754-41-0 structure

Name: Rezafungin acetate
Chemical Name: Rezafungin acetate
CAS Number: 1631754-41-0
Molecular Formula: C₆₅H₈₈N₈O₁₉
Molecular Weight: 1285.44
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2020-04-09 14:17:42
Modify Date: 2024-01-13 15:04:45
Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].

Name	Rezafungin acetate

Description	Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vivo	Rezafungin acetate (Biafungin acetate) (1 mg/kg; i.p. once daily for 6 days) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model[1]. Animal Model: C3H/HeN mice[1] Dosage: 1 mg/kg Administration: Intraperitoneal injection; once daily for 6 days Result: Significantly reduced nuclei and asci burdens.
References	[1]. Melanie Cushion, et al. Rezafungin Prophylactic Efficacy in a Mouse Model of Pneumocystis Pneumonia. VOLUME 25, ISSUE 3, SUPPLEMENT, S366, MARCH 01, 2019. [2]. Sofjan AK, et al. Rezafungin (CD101), a next-generation echinocandin: A systematic literature review and assessment of possible place in therapy. J Glob Antimicrob Resist. 2018 Sep;14:58-64.

Molecular Formula	C₆₅H₈₈N₈O₁₉
Molecular Weight	1285.44