2141981-87-3

2141981-87-3 structure

Name: TCO-PEG2-amine
Chemical Name: TCO-PEG2-amine
CAS Number: 2141981-87-3
Molecular Formula: C₁₅H₂₈N₂O₄
Molecular Weight: 300.39
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-11 23:57:18
Modify Date: 2024-01-02 17:29:48
TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	TCO-PEG2-amine

Description	TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.