2353409-94-4

2353409-94-4 structure

2353409-94-4 structure

Name: TCO-PEG6-amine
Chemical Name: TCO-PEG6-amine
CAS Number: 2353409-94-4
Molecular Formula: C₂₃H₄₄N₂O₈
Molecular Weight: 476.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-12 00:10:33
Modify Date: 2024-01-09 20:46:00
TCO-PEG6-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	TCO-PEG6-amine

Description	TCO-PEG6-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Molecular Formula	C₂₃H₄₄N₂O₈
Molecular Weight	476.60