2353409-95-5

2353409-95-5 structure
2353409-95-5 structure
  • Name: TCO-PEG8-NHS ester
  • Chemical Name: TCO-PEG8-NHS ester
  • CAS Number: 2353409-95-5
  • Molecular Formula: C32H54N2O14
  • Molecular Weight: 690.78
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-09 00:31:50
  • Modify Date: 2024-01-10 00:43:48
  • TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name TCO-PEG8-NHS ester
Description TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Molecular Formula C32H54N2O14
Molecular Weight 690.78