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658858-65-2

658858-65-2 structure
658858-65-2 structure
  • Name: THP-PEG9
  • Chemical Name: THP-PEG8-OH
  • CAS Number: 658858-65-2
  • Molecular Formula: C21H42O10
  • Molecular Weight: 454.55
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-12 17:37:43
  • Modify Date: 2024-01-08 11:32:24
  • THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name THP-PEG8-OH
Description THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C21H42O10
Molecular Weight 454.55
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